Mifepristone: Progesterone receptor antagonist (200mg oral dose) that blocks progesterone needed to maintain pregnancy.
Misoprostol: Prostaglandin analogue (800mcg buccal/vaginal) that causes uterine contractions and cervical softening.
Medical abortion is 95-98% effective for pregnancies up to 9 weeks gestation when using the combined mifepristone-misoprostol regimen. Effectiveness decreases slightly with advancing gestational age. The misoprostol-only regimen is about 85% effective.
Common expected effects include:
Seek medical attention if:
Yes, but you should receive Rh immunoglobulin (RhoGAM) within 72 hours of the abortion if you're Rh negative, unless the father is also Rh negative. This prevents sensitization in future pregnancies.
Signs of successful abortion include:
About 2-5% of cases require additional treatment.
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